5ml per seam of bees, 50ml per hive. One bottle treats 10 hives
See photos for DEFRA pdf.
SUMMARY OF PRODUCT CHARACTERISTICS
1. NAME OF THE VETERINARY MEDICINAL PRODUCT
Api-Bioxal 0.71 g/g bee-hive liquid
2. QUALITATIVE AND QUANTITATIVE COMPOSITION
Each g contains:
Active substance:
0.71 g oxalic acid equivalent to 0.995 g of oxalic acid dihydrate
Excipients:
Qualitative composition of excipients and other
constituents
Silica, colloidal hydrated
White fine powder.
3. CLINICAL INFORMATION
3.1 Target species
Honey bees (Apis mellifera).
3.2 Indications for use for each target species
Treatment of varroosis caused by Varroa destructor in honey bees (Apis mellifera).
3.3 Contraindications
None.
3.4 Special warnings
For greatest efficacy, the veterinary medicinal product should only be used when the
quantity of brood in the colony is non-existent or at its lowest levels. Oxalic acid does
not penetrate wax so will not kill mites within capped brood and therefore the
presence of brood may noticeably reduce the efficacy of the veterinary medicinal
product. As such, the veterinary medicinal product should be used in winter or
following manipulation of the colony to produce a broodless state in summer (e.g. by
queen caging). With regard to summer treatments following queen caging, highest
levels of efficacy were achieved when a caging period of at least 25 days was used,
at which point the colonies were completely broodless. Despite proper treatment,
seriously damaged colonies may not survive due to the effects of varroa infestation.
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Revised: December 2025